- Drug discovery strategies based on plant-derived active pharmaceutical ingredients
- In vitro permeability models (PAMPA):
- Drug absorption modeling (eye, nasal, BBB, GI, etc.)
- Modeling of tissue-specific drug distribution (liver, lung, kidney, etc.)
- Investigation of free-radical processes in permeability models
- Physicochemical profiling in drug discovery:
- Improvement of in silico methods for molecules with poorly predictable pKa values
- Development of high-throughput lipophilicity (logP/D) measurement methods, investigation of their applicability
- Investigating drug metabolism using biomimetic (chemical) models