Research projects

  • Drug discovery strategies based on plant-derived active pharmaceutical ingredients
  • In vitro permeability models (PAMPA):
      • Drug absorption modeling (eye, nasal, BBB, GI, etc.)
      • Modeling of tissue-specific drug distribution (liver, lung, kidney, etc.)
      • Investigation of free-radical processes in permeability models
  • Physicochemical profiling in drug discovery:
      • Improvement of in silico methods for molecules with poorly predictable pKa values
      • Development of high-throughput lipophilicity (logP/D) measurement methods, investigation of their applicability
  • Investigating drug metabolism using biomimetic (chemical) models